Document Detail

Multivessel coronary thrombosis, acute myocardial infarction, and no reflow in a patient with essential thrombocythaemia.
MedLine Citation:
PMID:  10814644     Owner:  NLM     Status:  MEDLINE    
Essential thrombocythaemia (ET) has been reported rarely to cause coronary thrombosis, but the management is still undefined. A 63 year old woman with multivessel coronary thrombosis, acute myocardial infarction (MI), and no reflow in reperfused coronary artery in association with ET is presented. The patient's platelet count was only moderately raised at the onset of MI, but peripheral blood smear and bone marrow evaluation revealed clumping giant platelets and numerous large hyperploid megakaryocytes. Long term prophylaxis with antiplatelet agents in patients with ET is recommended, even if the platelet count is not largely raised. Cytoreductive treatment may also be effective for secondary prevention when thrombotic complications occur.
H Terada; H Satoh; A Uehara
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Heart (British Cardiac Society)     Volume:  83     ISSN:  1468-201X     ISO Abbreviation:  Heart     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-07-06     Completed Date:  2000-07-06     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9602087     Medline TA:  Heart     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  E10     Citation Subset:  IM    
Division of Cardiology, Third Department of Internal Medicine, Hamamatsu University School of Medicine, 3600 Handa-cho, Hamamatsu 431-3192, Japan.
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MeSH Terms
Coronary Thrombosis / complications*,  radiography,  therapy
Megakaryocytes / pathology
Middle Aged
Myocardial Infarction / complications*,  radiography,  therapy
Myocardial Reperfusion
Platelet Aggregation
Thrombocytopenia / complications*,  radiography,  therapy

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