Document Detail

Multivariate mixed linear model analysis of longitudinal data: an information-rich statistical technique for analyzing plant disease resistance.
MedLine Citation:
PMID:  23046207     Owner:  NLM     Status:  In-Data-Review    
ABSTRACT The mixed linear model (MLM) is an advanced statistical technique applicable to many fields of science. The multivariate MLM can be used to model longitudinal data, such as repeated ratings of disease resistance taken across time. In this study, using an example data set from a multi-environment trial of northern leaf blight disease on 290 maize lines with diverse levels of resistance, multivariate MLM analysis was performed and its utility was examined. In the population and environments tested, genotypic effects were highly correlated across disease ratings and followed an autoregressive pattern of correlation decay. Because longitudinal data are often converted to the univariate measure of area under the disease progress curve (AUDPC), comparisons between univariate MLM analysis of AUDPC and multivariate MLM analysis of longitudinal data were made. Univariate analysis had the advantage of simplicity and reduced computational demand, whereas multivariate analysis enabled a comprehensive perspective on disease development, providing the opportunity for unique insights into disease resistance. To aid in the application of multivariate MLM analysis of longitudinal data on disease resistance, annotated program syntax for model fitting is provided for the software ASReml.
Yogasudha Veturi; Kristen Kump; Ellie Walsh; Oliver Ott; Jesse Poland; Judith M Kolkman; Peter J Balint-Kurti; James B Holland; Randall J Wisser
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Phytopathology     Volume:  102     ISSN:  0031-949X     ISO Abbreviation:  Phytopathology     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9427222     Medline TA:  Phytopathology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1016-25     Citation Subset:  IM    
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