| Multivariate Analysis of Morphometric Characteristics to Evaluate Risk Factors for Cranial Cruciate Ligament Deficiency in Labrador Retrievers. | |
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MedLine Citation:
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PMID: 21314700 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objectives: To determine the combination of conformation characteristics of the pelvic limbs of Labrador Retrievers that best discriminates between limb at risk to develop cranial cruciate ligament (CCL) disease and limbs at low risk using radiographs, computerized tomography (CT) images, and dual-energy X-ray absorptiometry (DEXA). Study Design: Cross-sectional clinical study. Animals: Twelve clinically normal and 9 unilaterally CCL-deficient Labrador Retrievers. Methods: The pelvic limbs of normal dogs were considered as non-predisposed to CCL disease and the contralateral limbs of CCL-deficient dogs as predisposed. Conformation variables, obtained from femur and tibial radiographs, pelvic limb CT images and DEXA studies, of predisposed pelvic limbs were compared with the conformation variables from pelvic limbs of the low-risk group. An ROC curve analysis was used to assess the discriminating properties of conformation variables for several combinations. Results: We determined that a combination of tibial plateau angle (TPA) and femoral anteversion angle (FAA) measured on radiographs was optimal for discriminating predisposed and non-predisposed limbs for CCL disease in Labrador Retrievers. Conclusions: Assessing predisposition to CCL disease with a combination of conformational measurements is better than using univariate parameters. In the future, TPA and FAA may be used to screen dogs suspected of being susceptible to CCL disease. |
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Authors:
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Chantal A Ragetly; Richard Evans; Ayman A Mostafa; Dominique J Griffon |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-2-11 |
Journal Detail:
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Title: Veterinary surgery : VS : the official journal of the American College of Veterinary Surgeons Volume: - ISSN: 1532-950X ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-2-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8113214 Medline TA: Vet Surg Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© Copyright 2011 by The American College of Veterinary Surgeons. |
Affiliation:
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Department of Small Animal Surgery, University of Illinois, Urbana, IL Department of Surgery, Cairo University, Giza, Egypt. |
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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