Document Detail

Multivalent interactions at interfaces.
MedLine Citation:
PMID:  17005436     Owner:  NLM     Status:  MEDLINE    
Multivalency describes the interaction between multivalent receptors and multivalent ligands. It plays a pivotal role in biochemistry, particularly in protein-carbohydrate interactions, both in solution and at interfaces. At interfaces in particular, multivalency is often poorly understood in a quantitative sense. Research on multivalency is currently an interplay of the fields of biochemistry and supramolecular chemistry. On the one hand, the understanding of supramolecular interactions at interfaces provides a tool for the quantitative description of multivalency at interfaces. On the other hand, the multivalent design rules developed in biological chemistry are applied in novel supramolecular nanostructures. The current review focuses on the former perspective (i.e. the use of well defined supramolecular platforms that function as model systems for understanding multivalent phenomena at interfaces).
Jurriaan Huskens
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2006-09-26
Journal Detail:
Title:  Current opinion in chemical biology     Volume:  10     ISSN:  1367-5931     ISO Abbreviation:  Curr Opin Chem Biol     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-12-04     Completed Date:  2007-02-13     Revised Date:  2009-08-25    
Medline Journal Info:
Nlm Unique ID:  9811312     Medline TA:  Curr Opin Chem Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  537-43     Citation Subset:  IM    
Molecular Nanofabrication Group & Strategic Research Orientation Nanofabrication MESA+ Institute for Nanotechnology, University of Twente PO Box 217, 7500 AE Enschede, The Netherlands.
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MeSH Terms
Cyclodextrins / chemistry
Models, Biological*
Models, Chemical*
Reg. No./Substance:

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