Document Detail

Multivalent Nanofibers of a Controlled Length: Regulation of Bacterial Cell Agglutination.
MedLine Citation:
PMID:  22924982     Owner:  NLM     Status:  Publisher    
The control of the size and shape of molecular assemblies on the nanometer scale in aqueous solutions is very important for the regulation of biological functions. Among the well-defined supramolecular structures of organic amphiphiles, 1-D nanofibers have attracted much attention due to their potential applications in biocompatible materials. Although much progress has been made in the field of self-assembled nanofibers, the ability to control fiber length remains limited. The approach to control fiber length presented herein overcomes this limitation through the co-assembly of amphiphilic rod-coil molecules in which the crystallinity of the aromatic segment can be regulated by π-π stacking interactions. The introduction of carbohydrate segments into the fiber exterior endows the nanofibers with the ability to adhere to bacterial cells. Notably, the fiber length systematically regulates the agglutination and proliferation of bacterial cells exposed to these fibers.
Dong-Woo Lee; Taehoon Kim; Il-Soo Park; Zhegang Huang; Myongsoo Lee
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-24
Journal Detail:
Title:  Journal of the American Chemical Society     Volume:  -     ISSN:  1520-5126     ISO Abbreviation:  J. Am. Chem. Soc.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503056     Medline TA:  J Am Chem Soc     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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