Document Detail


Multivalency in supramolecular chemistry and nanofabrication.
MedLine Citation:
PMID:  15565230     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Multivalency is a powerful and versatile self-assembly pathway that confers unique thermodynamic and kinetic behavior onto supramolecular complexes. The diversity of the examples of supramolecular multivalent systems discussed in this perspective shows that the concept of multivalency is a general phenomenon, and that any supramolecular interaction can be employed in multivalent displays to attain the attractive aspects characteristic of multivalent interactions. After a general introduction reviewing the general aspects of multivalency, a number of different supramolecular multivalent complexes are discussed that highlight the different features of multivalent interactions. In contrast to the many biochemical multivalent interactions, supramolecular multivalent interactions are ideal to attain a quantitative and fundamental understanding of multivalency. Several examples in which multivalency has been utilized in supramolecular nanofabrication schemes are described in detail.
Authors:
Alart Mulder; Jurriaan Huskens; David N Reinhoudt
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2004-11-05
Journal Detail:
Title:  Organic & biomolecular chemistry     Volume:  2     ISSN:  1477-0520     ISO Abbreviation:  Org. Biomol. Chem.     Publication Date:  2004 Dec 
Date Detail:
Created Date:  2004-11-26     Completed Date:  2005-02-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101154995     Medline TA:  Org Biomol Chem     Country:  England    
Other Details:
Languages:  eng     Pagination:  3409-24     Citation Subset:  IM    
Affiliation:
Laboratory of Supramolecular Chemistry and Technology, MESA+ Institute for Nanotechnology, University of Twente, P.O. Box 217, 7500 AE, Enschede, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Alanine / chemistry
Cyclodextrins / chemistry
Nanotechnology*
Vancomycin / chemistry
Chemical
Reg. No./Substance:
0/Cyclodextrins; 1404-90-6/Vancomycin; 56-41-7/Alanine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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