Document Detail

Multispectral fluorescence imaging.
MedLine Citation:
PMID:  19759119     Owner:  NLM     Status:  MEDLINE    
Multispectral fluorescence imaging (MSFI) is a rapidly growing field with broad applications in both preclinical and clinical settings. Application of this novel technology in small-animal imaging and microscopy produces enhanced sensitivity and reliable quantification and resolves multiple simultaneous signals. MSFI flow cytometry can quantify multiple fluorescent parameters with morphologic or subcellular spatial details on millions of cells. MSFI has the potential to improve the accuracy of disease detection or differentiation and intrasurgical metastatic diagnosis, guide neurosurgeries, and monitor treatment response.
Lanlan Zhou; Wafik S El-Deiry
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Publication Detail:
Type:  Journal Article; Review     Date:  2009-09-16
Journal Detail:
Title:  Journal of nuclear medicine : official publication, Society of Nuclear Medicine     Volume:  50     ISSN:  1535-5667     ISO Abbreviation:  J. Nucl. Med.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-01     Completed Date:  2009-11-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0217410     Medline TA:  J Nucl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1563-6     Citation Subset:  IM    
Department of Bioengineering, University of Pennsylvania School of Engineering and Applied Science, Philadelphia, Pennsylvania, USA.
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MeSH Terms
Brain / blood supply,  pathology
Diagnostic Imaging / methods*
Flow Cytometry
Neoplasms / blood supply,  diagnosis,  drug therapy
Quantum Dots
Spectrometry, Fluorescence / methods*

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