| Multislice spiral computed tomography to determine the effects of a recruitment maneuver in experimental lung injury. | |
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MedLine Citation:
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PMID: 16220208 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although recruitment of atelectatic lung is a common aim in acute respiratory distress syndrome (ARDS), the effects of a recruitment maneuver have not been assessed quantitatively. By multislice spiral CT (MSCT), we analyzed the changes in lung volumes calculated from the changes in the CT values of hyperinflated (V(HYP)), normally (V(NORM)), poorly (V(POOR)) and nonaerated (V(NON)) lung in eight mechanically ventilated pigs with saline lavage-induced acute lung injury before and after a recruitment maneuver. This was compared to single slice analysis near the diaphragm. The increase in aerated lung was mainly for V(POOR) and the less in V(NORM). Total lung volume and intrathoracic gas increased. No differences were found for tidal volumes measured by spirometry or determined by CT. The inspiratory-expiratory volume differences were not different after the recruitment maneuver in V(NON) (from 62+/-18 ml to 43+/-26 ml, P = 0.114), and in V(NORM) (from 216+/-51 ml to 251+/-37 ml, P = 0.102). Single slice analysis significantly underestimated the increase in normally and poorly aerated lung. Quantitative analysis of lung volumes by whole lung MSCT revealed the increase of poorly aerated lung as the main mechanism of a standard recruitment maneuver. MSCT can provide additional information as compared to single slice CT. |
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Authors:
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Dietrich Henzler; Andreas H Mahnken; Joachim E Wildberger; Rolf Rossaint; Rolf W Günther; Ralf Kuhlen |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2005-10-12 |
Journal Detail:
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Title: European radiology Volume: 16 ISSN: 0938-7994 ISO Abbreviation: Eur Radiol Publication Date: 2006 Jun |
Date Detail:
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Created Date: 2006-06-05 Completed Date: 2006-11-22 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 1351-9 Citation Subset: IM |
Affiliation:
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Anesthesiology Department, University Hospital, RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany. mail@d-henzler.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Disease Models, Animal Exhalation / physiology Image Processing, Computer-Assisted / methods* Inhalation / physiology Lung / physiopathology*, radiography Pulmonary Atelectasis / physiopathology*, radiography Pulmonary Gas Exchange / physiology Pulmonary Ventilation / physiology Respiration* Respiration, Artificial Respiratory Distress Syndrome, Adult / physiopathology, radiography Swine Tidal Volume / physiology Tomography, Spiral Computed / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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