| Multislice computed tomography in planning nephron-sparing surgery in a prospective study with 76 patients: comparison of radiological and histopathological findings in the infiltration of renal structures. | |
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MedLine Citation:
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PMID: 17082687 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The aim of this prospective study is to determine the diagnostic accuracy of multidetector-row computed tomography (CT) compared to histopathologic findings in tumor staging of renal cell carcinoma, with the focus on tumor stage, vein and artery infiltration, and infiltration of the renal pelvis. MATERIALS AND METHODS: In a prospective study, a total of 76 consecutive patients with suspected renal cell carcinoma were preoperatively assessed for tumor staging using multidetector-row CT. Triphasic CT imaging (i.e., noncontrast, arterial, and parenchymal phase) was performed using multidetector-row CT with reconstructed slice thicknesses of 2 and 5 mm. Two blinded readers evaluated the CT scans independently; the results were then correlated with the histopathologic results. RESULTS: A total of 56 renal cell carcinomas were proven on histopathology. Readers 1 and 2 reached a sensitivity of 1.0 and 1.0 and a specificity of 0.41 and 0.42 for arterial infiltration, a sensitivity of 1.0 and 0.86 and a specificity of 0.58 and 0.5 for venous infiltration, and a sensitivity of 0.75 and 1.0 and a specificity of 0.5 and 0.44 for infiltration of the renal pelvis. The correlation between both readers was 0.7 for all modalities. CONCLUSIONS: The multiplanar reconstruction capability of multidetector-row CT allowed good sensitivity in predicting arterial infiltration. The lowest specificity was reached in excluding infiltration of the renal pelvis. Despite its high temporal and spatial resolution, the capacity of multidetector CT to predict intrarenal infiltrations is still limited. |
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Authors:
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Peter Hallscheidt; Nina Wagener; Farshad Gholipour; Nastaran Aghabozorgi; Jens Dreyhaupt; Markus Hohenfellner; Axel Haferkamp; Jesco Pfitzenmaier |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of computer assisted tomography Volume: 30 ISSN: 0363-8715 ISO Abbreviation: J Comput Assist Tomogr Publication Date: 2006 Nov-Dec |
Date Detail:
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Created Date: 2006-11-03 Completed Date: 2007-01-03 Revised Date: 2007-02-12 |
Medline Journal Info:
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Nlm Unique ID: 7703942 Medline TA: J Comput Assist Tomogr Country: United States |
Other Details:
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Languages: eng Pagination: 869-74 Citation Subset: IM |
Affiliation:
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Department of Diagnostic Radiology, University of Heidelberg, Germany. hallscheidt@yahoo.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Carcinoma, Renal Cell / pathology*, radiography*, surgery Female Humans Kidney Neoplasms / pathology*, radiography*, surgery Male Middle Aged Nephrectomy / methods* Nephrons Prospective Studies Reproducibility of Results Tomography, X-Ray Computed* / methods |
| Comments/Corrections | |
Erratum In:
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J Comput Assist Tomogr. 2007 Jan-Feb;31(1):164 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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