Document Detail

Multisession CyberKnife radiosurgery for optic nerve sheath meningiomas.
MedLine Citation:
PMID:  18081476     Owner:  NLM     Status:  MEDLINE    
Optic nerve sheath meningiomas (ONSMs) are benign lesions originating from the dural sheath of the optic nerve. Progressive growth can lead to gradual loss of vision and exophthalmos. Loss of vision following microsurgical resection is not uncommon, and although stereotactic fractionated radiotherapy can be a safe alternative to control tumor growth and preserve vision, it may also lead to complications. Frame-based stereotactic radiosurgery has only been rarely used because single-fraction high-dose treatments of intrinsic optic nerve lesions may induce unacceptably high toxicity. New frameless radiosurgery devices such as the robotic CyberKnife, an image-guided radiosurgery system, can provide the extremely tight conformality and submillimetric accuracy of frame-based systems combined with the possibility of delivering radiation in several sessions. In the present report the authors review the clinical presentation and management of ONSMs and describe their preliminary experience using multisession radiosurgery to treat these lesions.
Pantaleo Romanelli; Berndt Wowra; Alexander Muacevic
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Neurosurgical focus     Volume:  23     ISSN:  1092-0684     ISO Abbreviation:  Neurosurg Focus     Publication Date:  2007  
Date Detail:
Created Date:  2007-12-17     Completed Date:  2008-02-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100896471     Medline TA:  Neurosurg Focus     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E11     Citation Subset:  IM    
Functional Neurosurgery, IRCCS Neuromed, Pozzilli, Italy.
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MeSH Terms
Follow-Up Studies
Meningeal Neoplasms / radiotherapy,  surgery*
Meningioma / radiotherapy,  surgery*
Middle Aged
Optic Nerve Neoplasms / radiotherapy,  surgery*
Radiation Dosage
Radiosurgery / methods*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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