Document Detail


Multiresidue analysis of antibiotics in food of animal origin using liquid chromatography-mass spectrometry.
MedLine Citation:
PMID:  21643913     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Antibiotics are the most important drugs administered in veterinary medicine. Their use in food-producing animals may result in antibiotic residues in edible tissues, which are monitored to protect human and animal health, support the enforcement of regulations, provide toxicological assessment data, and resolve international trade issues. This chapter provides basic characterization of the most important classes of antibiotics used in food-producing animals (aminoglycosides, amphenicols, β-lactams, macrolides and lincosamides, nitrofurans, quinolones, sulfonamides, and tetracyclines), along with examples of practical liquid chromatographic-(tandem) mass spectrometric methods for analysis of their residues in food matrices of animal origin. The focus is on multiresidue methods that are favored by regulatory and other food testing laboratories for their ability to analyze residues of multiple compounds in a time- and cost-effective way.
Authors:
Katerina Mastovska
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  747     ISSN:  1940-6029     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2011  
Date Detail:
Created Date:  2011-06-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  267-307     Citation Subset:  IM    
Affiliation:
Greenfield Laboratories, Nutritional Chemistry and Food Safety, Covance Laboratories, Inc., Greenfield, IN, USA, Katerina.Mastovska@covance.com.
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