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Multipotential pituitary cells that contain adrenocorticotropin (ACTH) and other pituitary hormones.
MedLine Citation:
PMID:  18411176     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Anterior pituitary cells that contain adrenocorticotropin (ACTH) are morphologically and functionally heterogeneous. Immunolabeling has identified stellate subtypes with scattered or peripherally arranged granules, and ovoid or irregularly shaped cells with a denser accumulation of granules, which overlap morphologically with other cell types such as small gonadotropes or thyrotropes. Dual cytochemical labeling studies on the same or serial fields have identified cells that store ACTH with LH, FSH, TSH, or prolactin. Evidence is presented to suggest that they are multipotential cells with the capacity to augment corticotropes or one of the other cell populations.
Authors:
G V Childs
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Trends in endocrinology and metabolism: TEM     Volume:  2     ISSN:  1043-2760     ISO Abbreviation:  Trends Endocrinol. Metab.     Publication Date:    1991 May-Jun
Date Detail:
Created Date:  2008-04-15     Completed Date:  2009-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9001516     Medline TA:  Trends Endocrinol Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  112-7     Citation Subset:  -    
Affiliation:
Department of Anatomy and Neurosciences, University of Texas Medical Branch, Galveston, TX 77550, USA.
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