Document Detail

Multipolar mitosis in procaine-treated polyspermic sea urchin eggs and in eggs fertilized with UV-irradiated spermatozoa with a computer model to simulate the positioning of centrosomes.
MedLine Citation:
PMID:  1935990     Owner:  NLM     Status:  MEDLINE    
Procaine-treated eggs can be penetrated by more than one spermatozoon. Supernumerary male pronuclei can fuse with the female one giving raise to multipolar spindles or remain isolated within the egg's cytoplasm forming their own spindle. In all types of multiple mitotic figures (asters and spindles) the distribution of asters is equidistant either uniplanar or at maximum distance like at the apices of a polyhedron. Astral rays are not different from spindle fibers: they can attach to and attract chromosomes of "foreign" mitotic figures. When several mitotic figures are present in one egg, the partner asters are always of the same size, and microtubules of one aster never interdigitate with those of others. The hypothesis that positioning of centrosomes is brought about by spreading of a centrosome organizer in the form of an expanding calotte on the surface of the nucleus (Mazia, D., Int. Rev. Cytol. 100, 49-92 (1987)) is supported by a computer model.
G Czihak; M Kojima; J Linhart; H Vogel
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of cell biology     Volume:  55     ISSN:  0171-9335     ISO Abbreviation:  Eur. J. Cell Biol.     Publication Date:  1991 Aug 
Date Detail:
Created Date:  1991-12-10     Completed Date:  1991-12-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7906240     Medline TA:  Eur J Cell Biol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  255-61     Citation Subset:  IM    
Department of Genetics and Developmental Biology, University of Salzburg, Austria.
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MeSH Terms
Cell Nucleus / ultrastructure
Computer Simulation*
Ovum / cytology,  drug effects*
Procaine / pharmacology*
Sea Urchins
Spermatozoa / cytology*,  radiation effects
Reg. No./Substance:

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