| Multiply organ dysfunction syndrome due to tramadol intoxication alone. | |
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MedLine Citation:
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PMID: 19683139 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tramadol is a synthetic, centrally acting analgesic for the treatment of moderate to severe pain. It is widely used because of its efficacy and safety. A normal-dose tramadol has less adverse effects than other opioids. Multiply organ dysfunction syndrome due to tramadol intoxication is rare.We present a case of 19-year-old male patient who had multiply organ dysfunction syndrome due to oral tramadol alone. With a history of tramadol abuse for 6 months, the patient was found unconsciousness in bed 8 hours before hospitalization. A toxicologic analysis showed a tramadol blood concentration of 9.5 mg/L without toxic levels of other drugs. The patient developed deep coma, acute respiratory distress syndrome, hepatic and renal dysfunction,and shock in the first 24 hours after admission. With mechanical ventilation, hemoperfusion, and other supportive therapies, his overall status gradually improved and he was discharged 23 days later. |
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Authors:
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Sheng-Qi Wang; Chun-Sheng Li; Yu-Guo Song |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The American journal of emergency medicine Volume: 27 ISSN: 1532-8171 ISO Abbreviation: Am J Emerg Med Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-08-17 Completed Date: 2009-09-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309942 Medline TA: Am J Emerg Med Country: United States |
Other Details:
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Languages: eng Pagination: 903.e5-7 Citation Subset: IM |
Affiliation:
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Department of Emergency, Chao Yang Hospital, Capital Medical University, Beijing, PR China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Humans Male Multiple Organ Failure / chemically induced* Narcotics / adverse effects*, blood Opioid-Related Disorders / complications, therapy Poisoning / therapy Respiratory Distress Syndrome, Adult / chemically induced Tramadol / blood, poisoning* |
| Chemical | |
Reg. No./Substance:
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0/Narcotics; 27203-92-5/Tramadol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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