Document Detail

Multiplicative correction of subject effect as preprocessing for analysis of variance.
MedLine Citation:
PMID:  18334385     Owner:  NLM     Status:  MEDLINE    
The procedure of repeated-measures ANOVA assumes the linear model in which effects of both subjects and experimental conditions are additive. However, in electroencephalography and magnetoencephalography, there may be situations where subject effects should be considered to be multiplicative in amplitude. We propose a simple method to normalize such data by multiplying each subject's response by a subject-specific constant. This paper derives ANOVA tables for such normalized data. Present simulations show that this method performs ANOVA effectively including multiple comparisons provided that the data follows the multiplicative model.
Iku Nemoto; Masaya Abe; Makoto Kotani
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  IEEE transactions on bio-medical engineering     Volume:  55     ISSN:  0018-9294     ISO Abbreviation:  IEEE Trans Biomed Eng     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-12     Completed Date:  2008-04-15     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0012737     Medline TA:  IEEE Trans Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  941-8     Citation Subset:  IM    
Department of Information Environment, Tokyo Denki Universiy, Inzai, Chiba 270-1382, Japan.
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MeSH Terms
Analysis of Variance
Brain / physiology*
Data Interpretation, Statistical*
Diagnosis, Computer-Assisted / methods
Electroencephalography / methods*
Evoked Potentials / physiology*
Magnetoencephalography / methods*
Reproducibility of Results
Sensitivity and Specificity
Signal Processing, Computer-Assisted*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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