| Multiple system atrophy manifested as dizziness and imbalance: a report of two cases. | |
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MedLine Citation:
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PMID: 12937917 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Multiple system atrophy (MSA) is a progressive neurodegenerative disease of undetermined origin that occasionally manifests as dizziness and imbalance. It is not often considered in clinical situations, especially not by neuro-otological consultants. Hence, we report our recent experience with two cases of MSA. One is that of a 62-year-old man with MSA with a predominant cerebellar feature, and the other is that of a 72-year-old man with MSA with a predominant parkinsonian feature. The results of the syncopic study correlated with orthostatic hypotension. The neuro-otological study in both patients revealed an abnormal eye tracking test, abnormal optokinetic nystagmus test and loss of visual suppression in the caloric nystagmus. These indicate that the central vestibular system, e.g., the cerebellum or brain stem, is affected by MSA, contributing to dizziness and imbalance. Therefore, diagnosis of MSA should be kept in mind by neuro-otological consultants when dealing with patients with dizziness and imbalance, especially when this is accompanied by orthostatic hypotension. |
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Authors:
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Shou-Ren Wang; Yi-Ho Young |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't Date: 2003-03-12 |
Journal Detail:
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Title: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery Volume: 260 ISSN: 0937-4477 ISO Abbreviation: Eur Arch Otorhinolaryngol Publication Date: 2003 Aug |
Date Detail:
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Created Date: 2003-08-25 Completed Date: 2004-02-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9002937 Medline TA: Eur Arch Otorhinolaryngol Country: Germany |
Other Details:
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Languages: eng Pagination: 404-7 Citation Subset: IM |
Affiliation:
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Department of Otolaryngology, National Taiwan University Hospital, 1 Chang-te st., Taipei, Taiwan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Dizziness / etiology*, physiopathology Electronystagmography Evoked Potentials, Auditory Evoked Potentials, Auditory, Brain Stem Gait* Humans Magnetic Resonance Imaging Male Middle Aged Multiple System Atrophy / complications*, diagnosis*, physiopathology Parkinsonian Disorders / etiology Visual Pathways / physiopathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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