Document Detail

Multiple superficial basal cell carcinomata--topical imiquimod versus curette and cryotherapy.
MedLine Citation:
PMID:  15727358     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Superficial basal cell carcinoma can be successfully managed by means other than surgical excision. Nonexcisional approaches include topical imiquimod, and curette and cryotherapy (C&C). OBJECTIVE: This article discusses the management of an insulin dependent diabetic man aged 52 years presenting with 17 torso basal cell carcinomas (BCCs); mostly superficial BCCs (SBCCs). DISCUSSION: Half were treated with topical imiquimod. The remaining lesions were treated with curette and cryotherapy. All lesions resolved with proven histologic clearance. The patient considered C&C caused him less discomfort and disruption. He developed a late secondary infection in some sites treated with imiquimod. At 12 months there was no evidence of recurrence though new nodular BCCs and SBCCs had developed elsewhere on his upper torso. He has elected to have future SBCCs managed with C&C. While excisional surgery remains the benchmark management for nonmelanoma skin cancer, topical imiquimod and C&C are important options for treating SBCCs.
Anthony J Dixon
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Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article    
Journal Detail:
Title:  Australian family physician     Volume:  34     ISSN:  0300-8495     ISO Abbreviation:  Aust Fam Physician     Publication Date:    2005 Jan-Feb
Date Detail:
Created Date:  2005-02-24     Completed Date:  2005-04-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0326701     Medline TA:  Aust Fam Physician     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  49-52     Citation Subset:  IM    
Skincanceronly, Geelong, Victoria.
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MeSH Terms
Administration, Topical
Aminoquinolines / administration & dosage,  adverse effects,  therapeutic use*
Carcinoma, Basal Cell / drug therapy,  surgery,  therapy*
Middle Aged
Recurrence / prevention & control
Skin Neoplasms / drug therapy,  surgery,  therapy*
Treatment Outcome
Reg. No./Substance:
0/Aminoquinolines; 99011-02-6/imiquimod

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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