| Multiple sclerosis with and without CSF bands: clinically indistinguishable but immunogenetically distinct. | |
| | |
MedLine Citation:
|
PMID: 17000979 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We sought to determine whether Swedish patients with multiple sclerosis (MS) with and without oligoclonal bands (OCBs) in the CSF constitute distinct subpopulations, clinically and immunogenetically. Our findings indicate that OCB-negative MS shares the same clinical features as OCB-positive MS regarding female predominance, age at onset, proportion of primary progressive cases, rate of MRI positivity, and disease severity. Our HLA-DRB1 genotyping results suggest, however, that OCB-positive and OCB-negative MS are immunogenetically distinct. |
| | |
Authors:
|
Kerstin Imrell; Anne-Marie Landtblom; Jan Hillert; Thomas Masterman |
Related Documents
:
|
9787729 - Obesity as an epidemic: facing the challenge. 12361769 - Bioastronautics: optimizing human performance through research and medical innovations. 21883559 - Effect of a calcium hydroxide/chlorhexidine paste as intracanal dressing in human prima... 16600959 - How can nutrition education contribute to competency-based resident evaluation? 18060009 - Menorrhagia: a synopsis of management focusing on herbal and nutritional supplements, a... 15481739 - Probiotics and medical nutrition therapy. 12463899 - Smartquery: context-sensitive links to medical knowledge sources from the electronic pa... 3875259 - The hypertrophied antral-pyloric fold. 17365459 - Compliance with the rcog's guidelines on medical record keeping in female sterilisation... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Neurology Volume: 67 ISSN: 1526-632X ISO Abbreviation: Neurology Publication Date: 2006 Sep |
Date Detail:
|
Created Date: 2006-09-26 Completed Date: 2006-10-11 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0401060 Medline TA: Neurology Country: United States |
Other Details:
|
Languages: eng Pagination: 1062-4 Citation Subset: AIM; IM |
Affiliation:
|
Division of Neurology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. kerstin.imrell@ki.se |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Female HLA-DR Antigens / genetics Humans Immunoglobulin G / cerebrospinal fluid* Magnetic Resonance Imaging / methods Male Multiple Sclerosis / cerebrospinal fluid*, epidemiology, immunology* Odds Ratio Oligoclonal Bands / blood, cerebrospinal fluid*, immunology* Sweden / epidemiology |
| Chemical | |
Reg. No./Substance:
|
0/HLA-DR Antigens; 0/Immunoglobulin G; 0/Oligoclonal Bands; 128338-86-3/HLA-DRB1 antigen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: No indication of brain reorganization after unilateral ischemic lesions of the auditory cortex.
Next Document: Leukoencephalopathy induced by levamisole alone for the treatment of recurrent aphthous ulcers.