Document Detail

Multiple sclerosis progression is not associated with birth timing in Italy.
MedLine Citation:
PMID:  25194635     Owner:  NLM     Status:  Publisher    
BACKGROUND: Month of birth has been associated in some studies with the susceptibility to develop Multiple Sclerosis (MS). However, only few studies have evaluated whether birth timing also affects disease progression.
OBJECTIVES: To assess whether season and month of birth are associated with disease progression in a large cohort of Italian patients.
METHODS: Quantile regression was used to analyze the impact of each month and season of birth with all the others combined on the median Multiple Sclerosis Severity Score of 1866 MS patients.
RESULTS: No significant temporal trend was found after adjustment for multiple comparisons.
CONCLUSIONS: Birth timing showed no association with MS progression in Italian patients.
Ausiliatrice Lucenti; Stefania Galimberti; Nadia Barizzone; Paola Naldi; ; ; Giancarlo Comi; Filippo Martinelli Boneschi; Sandra D'Alfonso; Maurizio A Leone
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-8-23
Journal Detail:
Title:  Journal of the neurological sciences     Volume:  -     ISSN:  1878-5883     ISO Abbreviation:  J. Neurol. Sci.     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-9-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375403     Medline TA:  J Neurol Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier B.V. All rights reserved.
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