Document Detail

Multiple sclerosis and myasthenia gravis. A case report with single fiber electromyography.
MedLine Citation:
PMID:  945496     Owner:  NLM     Status:  MEDLINE    
A 34-year-old woman with long-standing multiple sclerosis had a 2-year history and physical signs of myasthenia gravis. The edrophonium chloride (Tensilon) test was positive. Repetitive stimulation of the ulnar nerve at 3 Hz did not show evidence of myasthenic response; however, a single-fiber electromyography demonstrated evidence of neuromuscular block as seen in myasthenia gravis, which was reversed to normal after intravenously administered edrophonium. The patient improved on anticholinesterase medication. It is suggested that patients with multiple sclerosis who have unusual features such as in the patient reported here should be investigated for the presence of myasthenia gravis to ensure proper treatment.
A N Achari; J V Trontelj; D J Campos
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neurology     Volume:  26     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1976 Jun 
Date Detail:
Created Date:  1976-09-02     Completed Date:  1976-09-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  544-6     Citation Subset:  IM    
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MeSH Terms
Diagnosis, Differential
Multiple Sclerosis / complications*,  diagnosis,  physiopathology
Muscles / physiopathology
Myasthenia Gravis / complications*,  diagnosis,  physiopathology
Neuromuscular Junction / physiology

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