Document Detail

Multiple sclerosis mortality and patterns of comorbidity in the United States from 1990 to 2001.
MedLine Citation:
PMID:  16374035     Owner:  NLM     Status:  MEDLINE    
Multiple sclerosis (MS) is a neurodegenerative condition that can result in cognitive and physical disability and shortened life expectancy. However, population-based information is lacking regarding the mortality burden from MS in the United States. We investigated trends in MS mortality rates and examined important comorbidities in the United States from 1990 to 2001. MS deaths were matched by age, sex, and race/ethnicity with randomly selected deaths from other conditions for matched odds ratio comparisons. The overall age-adjusted mortality rate from MS was 1.44/100,000 population. MS mortality rates increased throughout the study period. MS mortality rates were higher in whites than in any other racial/ethnic group, followed by Blacks, Hispanics, American Indians/Alaska Natives, and Asians and Pacific Islanders. Observed mortality rates were more than 10 times lower in Asians and Pacific Islanders than in whites. The odds of pressure ulcers, urinary tract infections, and pneumonia/influenza being reported on the death certificate were higher in MS deaths than in matched controls.
Matthew D Redelings; Lucie McCoy; Frank Sorvillo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2005-12-21
Journal Detail:
Title:  Neuroepidemiology     Volume:  26     ISSN:  0251-5350     ISO Abbreviation:  Neuroepidemiology     Publication Date:  2006  
Date Detail:
Created Date:  2006-02-07     Completed Date:  2006-03-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8218700     Medline TA:  Neuroepidemiology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  102-7     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2006 S. Karger AG, Basel.
Los Angeles County Department of Health Services, School of Public Health, University of California at Los Angeles, Los Angeles, CA , USA.
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MeSH Terms
Age Factors
Aged, 80 and over
Child, Preschool
Continental Population Groups
Ethnic Groups
Infant, Newborn
Middle Aged
Mortality / trends
Multiple Sclerosis / complications*,  mortality*
Odds Ratio
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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