Document Detail


Multiple sclerosis in a nationwide series of twins.
MedLine Citation:
PMID:  3658169     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A nation wide Finnish Twin Cohort was linked with sickness insurance and hospital discharge registers on the basis of the unique identification number assigned to each Finnish citizen. The study series consisted of 4,063 monozygotic (MZ) and 9,001 dizygotic (DZ) same-sexed twin pairs born before 1958 and alive in 1981. Altogether, 22 subjects representing 11 MZ pairs and 10 DZ pairs showed clinically definite multiple sclerosis (MS). In one MZ pair both members had the disease. The frequency of MS among DZ twins corresponded to the figure in the Finnish population, but the prevalence was higher in MZ twins than in DZ twins.
Authors:
E Kinnunen; M Koskenvuo; J Kaprio; K Aho
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurology     Volume:  37     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1987 Oct 
Date Detail:
Created Date:  1987-11-03     Completed Date:  1987-11-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1627-9     Citation Subset:  AIM; IM    
Affiliation:
National Public Health Institute, Helsinki, Finland.
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MeSH Terms
Descriptor/Qualifier:
Adult
Diseases in Twins*
Female
Humans
Male
Middle Aged
Multiple Sclerosis / genetics*
Twins, Dizygotic
Twins, Monozygotic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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