Document Detail


Multiple sclerosis in Malaysia.
MedLine Citation:
PMID:  3369969     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thirty consecutive patients from peninsular Malaysia with clinically definite multiple sclerosis were studied; 80% were ethnic Chinese, with a female-male ratio of 5:1. The average age at onset was 29.7 years, with one relapse average every 1.9 years. Optic-spinal recurrence was the most common clinical pattern of the disease, accounting for 63.3% (19/30) of the cases. All the patients had spinal cord involvement sometime during the course of the illness. The mortality was high at 36.7% (11/30), with an average duration of symptoms of 7.6 years. There was characteristic severe residual visual and motor disability. At the time of the last examination, 12 patients had bilateral optic atrophy with blindness or severe visual acuity impairment. Sixteen patients were bedridden or confined to a wheelchair. The severe motor disability reflected the severe spinal cord involvement. It was the main factor that accounted for the high mortality. The cerebral, cerebellar, and brain-stem involvements were, however, generally transient. None of the patients' had a family history of similar illness despite the average sibling size of six. There was no example of Devic's disease. The clinical pattern was closest to those patients who presented from Taiwan.
Authors:
C T Tan
Related Documents :
9496149 - Pyogenic, tuberculous, and brucellar vertebral osteomyelitis: a descriptive and compara...
17899109 - Fiber density index, fractional anisotropy, adc and clinical motor findings in the whit...
12690529 - Intramedullary spinal cord cavernous malformations: clinical features and risk of hemor...
16793729 - Combined protocol of cell therapy for chronic spinal cord injury. report on the electri...
8578379 - Chemonucleolysis versus laminectomy. a cohort comparison of effectiveness and charges.
3873709 - Trimethoprim-sulfamethoxazole, pseudomembranous colitis, and spinal cord injury.
24748479 - Protective effect of preserved bladder-filling sensation on upper urinary tract in pati...
2107999 - Use of capnography in diagnosis of pulmonary embolism during acute respiratory failure ...
20015799 - Clinicopathologic similarities between mikulicz disease and küttner tumor.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of neurology     Volume:  45     ISSN:  0003-9942     ISO Abbreviation:  Arch. Neurol.     Publication Date:  1988 Jun 
Date Detail:
Created Date:  1988-06-23     Completed Date:  1988-06-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372436     Medline TA:  Arch Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  624-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
China / ethnology
Female
Humans
Malaysia
Male
Multiple Sclerosis / complications*,  epidemiology
Nervous System Diseases / etiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Multiple sclerosis, solvents, and pets. A case-referent study.
Next Document:  Atypical psychosis with disseminated subpial demyelination.