| Multiple sclerosis in Malaysia. | |
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MedLine Citation:
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PMID: 3369969 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirty consecutive patients from peninsular Malaysia with clinically definite multiple sclerosis were studied; 80% were ethnic Chinese, with a female-male ratio of 5:1. The average age at onset was 29.7 years, with one relapse average every 1.9 years. Optic-spinal recurrence was the most common clinical pattern of the disease, accounting for 63.3% (19/30) of the cases. All the patients had spinal cord involvement sometime during the course of the illness. The mortality was high at 36.7% (11/30), with an average duration of symptoms of 7.6 years. There was characteristic severe residual visual and motor disability. At the time of the last examination, 12 patients had bilateral optic atrophy with blindness or severe visual acuity impairment. Sixteen patients were bedridden or confined to a wheelchair. The severe motor disability reflected the severe spinal cord involvement. It was the main factor that accounted for the high mortality. The cerebral, cerebellar, and brain-stem involvements were, however, generally transient. None of the patients' had a family history of similar illness despite the average sibling size of six. There was no example of Devic's disease. The clinical pattern was closest to those patients who presented from Taiwan. |
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Authors:
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C T Tan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of neurology Volume: 45 ISSN: 0003-9942 ISO Abbreviation: Arch. Neurol. Publication Date: 1988 Jun |
Date Detail:
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Created Date: 1988-06-23 Completed Date: 1988-06-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372436 Medline TA: Arch Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 624-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult China / ethnology Female Humans Malaysia Male Multiple Sclerosis / complications*, epidemiology Nervous System Diseases / etiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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