Document Detail


Multiple sclerosis is a chronic central nervous system infection by a spirochetal agent.
MedLine Citation:
PMID:  3357458     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Multiple Sclerosis (MS) is a chronic central nervous system (CNS) infection similar to Lyme Disease or Neurosyphilis in its latency period, pathogenesis, symptoms, histopathology and chronic CNS involvement. It does not have as yet a fully identified spirochetal etiological agent. Much research and clinical support for this hypothesis was published before 1954 and is based on silver staining of neural lesions, animal isolation of the etiologic agent and the characteristic symptoms and pathogenesis of the disease. If this hypothesis is correct, the disease should be treatable with antibacterial agents that penetrate the CNS (such as high dose antibiotics), diagnosible by specific immunological tests, and preventable by early treatment or by the use of vaccines in high risk populations.
Authors:
V Marshall
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical hypotheses     Volume:  25     ISSN:  0306-9877     ISO Abbreviation:  Med. Hypotheses     Publication Date:  1988 Feb 
Date Detail:
Created Date:  1988-05-16     Completed Date:  1988-05-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505668     Medline TA:  Med Hypotheses     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  89-92     Citation Subset:  IM    
Affiliation:
Animal Vaccine Laboratory, Council Bluffs, Iowa 51501.
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MeSH Terms
Descriptor/Qualifier:
Animals
Humans
Multiple Sclerosis / etiology*
Spirochaetales Infections*

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