| Multiple sclerosis and the autonomic nervous system. | |
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MedLine Citation:
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PMID: 16477481 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Symptoms related to alterations of the autonomic nervous system are frequent in patients with multiple sclerosis (MS). Bladder or bowel dysfunction or impairment of sexual performance is highly distressing for most MS patients,whereas the clinical relevance of other autonomic symptoms is less clear. Cardiovascular autonomic alterations might relate to clinical signs such as orthostatic intolerance; a relationship with fatigue is uncertain. However, the frequency of abnormal findings in tests for the cardiovascular autonomic system varies due to the lack of standardized test performance or differentially used cut-off values. The incidence of additional symptoms such as pupillomotor or sweating alterations and especially their relationship to overall autonomic nervous system abnormalities is not well known. Although their impact on daily life is low, they can at least serve as diagnostic tools. Beside these clinical aspects, alterations of the autonomic nervous system have also been reported to alter immunological cascades in experimental conditions. However, corresponding results have not been confirmed in clinical trials yet. |
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Authors:
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Stefan Merkelbach; Carl-Albrecht Haensch; Bernhard Hemmer; Jürgen Koehler; Nicolaus H König; Tjalf Ziemssen |
Publication Detail:
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Type: Consensus Development Conference; Journal Article |
Journal Detail:
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Title: Journal of neurology Volume: 253 Suppl 1 ISSN: 0340-5354 ISO Abbreviation: J. Neurol. Publication Date: 2006 Feb |
Date Detail:
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Created Date: 2006-02-14 Completed Date: 2006-04-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0423161 Medline TA: J Neurol Country: Germany |
Other Details:
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Languages: eng Pagination: I21-5 Citation Subset: IM |
Affiliation:
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Dept. of Neurology, HELIOS-Klinikum, Nordhäuser Str. 74, 99089, Erfurt, Germany. smerkelbach@erfurt.helios-kliniken.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Autonomic Nervous System
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physiopathology* Autonomic Nervous System Diseases / etiology*, physiopathology* Body Temperature Regulation / physiology Cardiovascular Diseases / etiology, physiopathology Humans Multiple Sclerosis / complications*, physiopathology* Pupil / physiology Sweating / physiology Urinary Bladder Diseases / etiology, physiopathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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