| Multiple sclerosis, acute disseminated encephalomyelitis, and related conditions. | |
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MedLine Citation:
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PMID: 10914409 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Multiple sclerosis (MS) and acute disseminated encephalomyelitis (ADEM) are conditions whose closely related pathology suggests shared pathophysiological elements, but whose clinical courses are usually, but not always quite dissimilar. The former is largely a disease of adulthood, the latter of childhood. Optic neuritis, demyelinative transverse myelitis, and Devic's syndrome are neurological syndromes that may occur as manifestations of either MS or ADEM. Patients with Miller-Fisher syndrome and encephalomyelradiculoneuropathy usually have features suggesting ADEM in combination with acute demyelinative polyneuropathy. These various conditions and other forms of ADEM share an indistinct border with encephalitides, granulomatous, and vasculitic conditions. MS, ADEM, and the pertinent syndromic subtypes, their differential diagnosis, treatment, and prognosis are considered in this review. Acute cerebellar ataxia is a syndrome that is likely to be pathophysiologically distinct from ADEM, although its occurrence as a postinfectious illness suggests a distant kinship. It is also reviewed. |
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Authors:
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R S Rust |
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Publication Detail:
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Type: Comparative Study; Journal Article; Review |
Journal Detail:
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Title: Seminars in pediatric neurology Volume: 7 ISSN: 1071-9091 ISO Abbreviation: Semin Pediatr Neurol Publication Date: 2000 Jun |
Date Detail:
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Created Date: 2000-12-07 Completed Date: 2000-12-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9441351 Medline TA: Semin Pediatr Neurol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 66-90 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, University of Virginia School of Medicine, Charlottesville 22903, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Brain / pathology*, physiopathology* Cerebellar Ataxia / diagnosis*, therapy Diagnosis, Differential Encephalomyelitis, Acute Disseminated / diagnosis*, physiopathology*, therapy Humans Leukoencephalitis, Acute Hemorrhagic / diagnosis*, therapy Multiple Sclerosis / diagnosis*, physiopathology*, therapy Myelitis, Transverse / diagnosis*, therapy Neuromyelitis Optica / diagnosis*, therapy Optic Neuritis / diagnosis*, therapy Prognosis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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