| Multiple sclerosis. TNFRSF1A, TRAPS and multiple sclerosis. | |
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MedLine Citation:
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PMID: 19794511 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A genome-wide association study has identified the R92Q variant of the TNFRSF1A gene as a new susceptibility locus for multiple sclerosis. This locus is of special interest because the R92Q substitution was previously detected in a group of multiple sclerosis patients who had additional symptoms compatible with the autoinflammatory syndrome TRAPS. |
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Authors:
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Tania K??mpfel; Reinhard Hohlfeld |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Nature reviews. Neurology Volume: 5 ISSN: 1759-4766 ISO Abbreviation: Nat Rev Neurol Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-10-01 Completed Date: 2009-12-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101500072 Medline TA: Nat Rev Neurol Country: England |
Other Details:
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Languages: eng Pagination: 528-9 Citation Subset: IM |
Affiliation:
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Institute of Clinical Neuroimmunology-Campus Grosshadern, Ludwig Maximilians University of Munich, Marchioninistrasse 15, Munich, Germany. tania.kuempfel@med.uni-muenchen.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Autoimmune Diseases
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genetics*,
immunology Genetic Predisposition to Disease* Genome-Wide Association Study Humans Multiple Sclerosis / genetics*, immunology Receptors, Tumor Necrosis Factor / genetics, immunology Receptors, Tumor Necrosis Factor, Type I / genetics*, immunology Signal Transduction / genetics, immunology Syndrome Tumor Necrosis Factor-alpha / genetics, immunology |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Tumor Necrosis Factor; 0/Receptors, Tumor Necrosis Factor, Type I; 0/TNFRSF1A protein, human; 0/Tumor Necrosis Factor-alpha |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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