Document Detail


Multiple schwannomas, multiple nevi, and multiple vaginal leiomyomas: a new dominant syndrome.
MedLine Citation:
PMID:  9637429     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report on a family of seven affected with a new syndrome of multiple deep schwannomas, multiple nevi (both intradermal and compound types), and multiple leiomyomas of the vagina. Inheritance is dominant, whether autosomal or X-linked cannot be determined at this time. The nevi, which are congenital, appear to be a marker for the syndrome. Both the schwannomas and leiomyomas do not manifest until adulthood.
Authors:
R J Gorlin; I G Koutlas
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of medical genetics     Volume:  78     ISSN:  0148-7299     ISO Abbreviation:  Am. J. Med. Genet.     Publication Date:  1998 Jun 
Date Detail:
Created Date:  1998-08-20     Completed Date:  1998-08-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7708900     Medline TA:  Am J Med Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  76-81     Citation Subset:  IM    
Affiliation:
Department of Oral Science, University of Minnesota School of Dentistry, Minneapolis 55455, USA. gorli002@maroon.tc.umn.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Female
Humans
Leiomyoma / genetics*
Male
Middle Aged
Neoplasms, Multiple Primary / genetics*
Neoplastic Syndromes, Hereditary / genetics*
Neurilemmoma / genetics*,  pathology
Nevus / genetics*
Pedigree
Skin Neoplasms / genetics*
Vaginal Neoplasms / genetics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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