Document Detail


Multiple players in mouse B cell memory.
MedLine Citation:
PMID:  23725874     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
B cell memory has long been considered the attribute of the sole IgG-positive B cell subset. Since a few years, and due to new B-cell subset identification procedures, increasing heterogeneity has been identified among the memory B cell pool. IgM-positive cells and germinal center-independent subsets are recent additions to the field. This review describes the diversity of memory B cells, as well as controversial issues on their relative contribution to the recall response. The impact of a protracted germinal center response to the specific mobilization of IgM memory B cells is proposed.
Authors:
Jean-Claude Weill; Simon Le Gallou; Yi Hao; Claude-Agnès Reynaud
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-5-28
Journal Detail:
Title:  Current opinion in immunology     Volume:  -     ISSN:  1879-0372     ISO Abbreviation:  Curr. Opin. Immunol.     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-6-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8900118     Medline TA:  Curr Opin Immunol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Elsevier Ltd. All rights reserved.
Affiliation:
INSERM U783 "Développement du système immunitaire", Université Paris Descartes, Faculté de Médecine, Site Broussais, 96 rue Didot, 75014 Paris, France. Electronic address: jean-claude.weill@inserm.fr.
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