| Multiple organ dysfunction syndrome: infection or hypersensitivity reaction? | |
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MedLine Citation:
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PMID: 19820401 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Anticonvulsant hypersensitivity syndrome is a potentially life-threatening delayed hypersensitivity reaction characterized by the triad of fever, rash and multiorgan involvement, which usually occurs within the first weeks of introduction of an antiepileptic drug. It mimics several life-threatening diseases, which makes it potentially difficult to recognize. We describe the case of a 6-year-old boy admitted with anticonvulsant hypersensitivity syndrome after the association of lamotrigine treatment with sodium valproic acid for reluctant epilepsy. |
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Authors:
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Alexandra Dreesman; Anne Hoorens; Said Hachimi-Idrissi |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: European journal of emergency medicine : official journal of the European Society for Emergency Medicine Volume: 17 ISSN: 1473-5695 ISO Abbreviation: Eur J Emerg Med Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-06-30 Completed Date: 2010-10-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9442482 Medline TA: Eur J Emerg Med Country: England |
Other Details:
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Languages: eng Pagination: 228-9 Citation Subset: IM |
Affiliation:
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Critical Care Department and Cerebral Resuscitation Research Group of the Universitair Ziekenhuis Brussel, Brussels, Belgium. Alexandra.Dreesman@uzbrussel.be |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anticonvulsants
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adverse effects* Child Drug Hypersensitivity / diagnosis, etiology*, therapy Drug Therapy, Combination Humans Hypersensitivity, Delayed / chemically induced*, diagnosis, therapy Male Multiple Organ Failure / chemically induced*, diagnosis, therapy Triazines / adverse effects* Valproic Acid / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants; 0/Triazines; 84057-84-1/lamotrigine; 99-66-1/Valproic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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