| Multiple neoplasms following craniospinal irradiation for medulloblastoma in a patient with nevoid basal cell carcinoma syndrome. Case report. | |
| | |
MedLine Citation:
|
PMID: 9010431 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A 28-year-old man presented to the authors' hospital with multiple intracranial tumors. At 2 years of age, he had undergone resection of a medulloblastoma and received adjunctive craniospinal irradiation. Subsequently, he was diagnosed with nevoid basal cell carcinoma syndrome, Gorlin's syndrome. Since his first presentation, he has required surgery for multiple basal cell carcinomas, an osteochondroma of the rib, two meningiomas, a trigeminal schwannoma, and a pleomorphic liposarcoma, all of which arose within the radiation field. Despite this impressive list of benign and malignant neoplasms, the patient is relatively well and leads a normal life. The authors examine the relationships between Gorlin's syndrome and radiation therapy and the subsequent development of tumors. |
| | |
Authors:
|
S O'Malley; D Weitman; M Olding; L Sekhar |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Journal of neurosurgery Volume: 86 ISSN: 0022-3085 ISO Abbreviation: J. Neurosurg. Publication Date: 1997 Feb |
Date Detail:
|
Created Date: 1997-02-13 Completed Date: 1997-02-13 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0253357 Medline TA: J Neurosurg Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 286-8 Citation Subset: AIM; IM |
Affiliation:
|
Department of Neurosurgery, George Washington University School of Medicine and Health Sciences, Washington, D.C., USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Basal Cell Nevus Syndrome / diagnosis, etiology*, surgery Bone Neoplasms / surgery Brain Neoplasms / etiology*, surgery Cerebellar Neoplasms / radiotherapy*, surgery Humans Liposarcoma / surgery Male Medulloblastoma / radiotherapy*, surgery Neoplasms, Radiation-Induced* / surgery Ribs |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Juvenile active ossifying fibroma. Report of four cases.
Next Document: Disappearing cervical disc. Case report.