| Multiple myeloma and systemic lupus erythematosus in a young woman. | |
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MedLine Citation:
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PMID: 19734735 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Although systemic lupus erythematosus (SLE) is associated with lymphoid malignancies, concurrent multiple myeloma and SLE are rare. We report a 28-year-old black woman with SLE who developed smoldering IgA kappa multiple myeloma. The coexistence of these conditions in this age and race has not been previously reported. A literature search was conducted and all 12 previously reported cases of concurrent SLE and multiple myeloma were reviewed. The demographic and clinical features of multiple myeloma in SLE are summarized. Possible mechanisms underlying this association are also discussed. In the appropriate clinical context, multiple myeloma should be considered in SLE patients irrespective of young age, race, SLE disease activity, or duration. |
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Authors:
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Kelechi Okoli; Farzan Irani; William Horvath |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases Volume: 15 ISSN: 1536-7355 ISO Abbreviation: J Clin Rheumatol Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-09-07 Completed Date: 2009-12-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9518034 Medline TA: J Clin Rheumatol Country: United States |
Other Details:
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Languages: eng Pagination: 292-4 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, St. Vincent Mercy Medical Center, Toledo, Ohio, USA. ofeokro@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Dexamethasone / therapeutic use Female Humans Immunoglobulin A / blood Immunosuppressive Agents / therapeutic use Lupus Erythematosus, Systemic / complications*, diagnosis*, drug therapy Multiple Myeloma / complications*, diagnosis*, immunology Thalidomide / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulin A; 0/Immunosuppressive Agents; 50-02-2/Dexamethasone; 50-35-1/Thalidomide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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