Document Detail

Multiple myeloma presenting as primary non-secretory plasma cell leukemia.
MedLine Citation:
PMID:  15027746     Owner:  NLM     Status:  MEDLINE    
Primary plasma cell leukemia is a rare manifestation of multiple myeloma, whose neoplastic hierarchy in the classification of malignant hematological disorders is not yet very clearly defined. Morphological and immunological criteria indicate that the cells are at end stage of B cell maturation pathway. This unusual disorder is diagnosed by the presence of more than 2 x 10(9) plasma cells per liter of peripheral blood or more than 20% of the leucocytes being plasma cells on differential count. This occurs either denovo or as a terminal event in patients with long standing multiple myeloma. A case report of a young male patient with primary plasma cell leukemia is presented.
Jitender Mohan Khunger; Mukesh Sharma; V H Talib
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Indian journal of pathology & microbiology     Volume:  46     ISSN:  0377-4929     ISO Abbreviation:  Indian J Pathol Microbiol     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2004-03-18     Completed Date:  2004-04-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7605904     Medline TA:  Indian J Pathol Microbiol     Country:  India    
Other Details:
Languages:  eng     Pagination:  104-5     Citation Subset:  IM    
Department of Haematology,VMMC & Safdarjang Hospital, New Delhi.
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MeSH Terms
Immunoglobulins / biosynthesis
Leukemia, Plasma Cell / immunology,  pathology*
Multiple Myeloma / immunology,  pathology*
Reg. No./Substance:
Comment In:
Indian J Pathol Microbiol. 2004 Oct;47(4):592-3   [PMID:  16295407 ]

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