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Multiple myeloma presenting as bilateral breast lumps in pregnant woman.
MedLine Citation:
PMID:  23975520     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Multiple myeloma (MM) is a systemic disease in the elderly. Its incidence in patients younger than 40 years old and especially in pregnant women is extremely rare. MM may involve extraosseous sites, and only in rare cases it is observed in the breast.
CASE REPORT: We describe the case of a 39-year-old woman diagnosed with an IgG lambda light-chain MM (Durie-Salmon stage IIIA, International Staging System II) in the 26th week of pregnancy, presenting with bilateral breast lumps. Dexamethasone (20 mg/m(2)/day on days 1-4, 9-12, and 17-20) was given as an induction agent to decrease tumor mass during pregnancy. Adverse response to dexamethasone was minor with excellent tolerance. A healthy baby was delivered at week 34 of gestation.
CONCLUSION: Breast nodules revealing MM are extremely rare. Clinical and radiological features are atypical. Presentation during pregnancy is extremely rare, making anti-MM treatment potentially challenging.
Authors:
Racem Bouzguenda; Afef Khanfir; Nabil Toumi; Kais Chaaben; Yosr Hentati; Lobna Ayadi; Wiem Feki; Jamel Daoud; Mounir Frikha
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-8-23
Journal Detail:
Title:  International journal of hematology     Volume:  -     ISSN:  1865-3774     ISO Abbreviation:  Int. J. Hematol.     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-8-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111627     Medline TA:  Int J Hematol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Medical Oncology, Habib Bourguiba University Hospital, 3029, Sfax, Tunisia, racem.bouzguenda@gmail.com.
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