Document Detail

Multiple myeloma: diagnosis and orthopaedic implications.
MedLine Citation:
PMID:  21724920     Owner:  NLM     Status:  MEDLINE    
Multiple myeloma is a hematologic malignancy that commonly affects the skeletal system. The disease is primarily managed medically with chemotherapeutic agents. Pathologic fractures are common in patients with diagnosed and undiagnosed disease. The number of patients diagnosed with multiple myeloma is increasing, as is the incidence of associated pathologic fractures. Novel chemotherapeutic agents and radiation therapy protocols have been used to extend the average life span of patients with this disease. Various methods that allow for restoration of function and pain reduction can be used to stabilize and manage fractures associated with multiple myeloma. The orthopaedic surgeon and oncology team must work together to develop an individualized treatment plan to improve patient quality of life and provide pain relief.
Thomas J Scharschmidt; Joshua D Lindsey; Pamela S Becker; Ernest U Conrad
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of the American Academy of Orthopaedic Surgeons     Volume:  19     ISSN:  1067-151X     ISO Abbreviation:  J Am Acad Orthop Surg     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-07-04     Completed Date:  2011-09-13     Revised Date:  2013-03-18    
Medline Journal Info:
Nlm Unique ID:  9417468     Medline TA:  J Am Acad Orthop Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  410-9     Citation Subset:  IM    
Department of Orthopaedic, Ohio State University College of Medicine, Columbus, OH, USA.
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MeSH Terms
Antineoplastic Agents / therapeutic use
Diagnosis, Differential
Fracture Fixation / methods*
Fractures, Spontaneous* / diagnosis,  etiology,  therapy
Magnetic Resonance Imaging / methods*
Multiple Myeloma* / complications,  diagnosis,  drug therapy
Treatment Outcome
Grant Support
Reg. No./Substance:
0/Antineoplastic Agents

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