| Multiple myeloma, IgA cryoglobulinemia and serum hyperviscosity in a dog. | |
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MedLine Citation:
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PMID: 591115 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Clinical signs of hyperviscosity syndrome in a 6-year-old dog included listlessness, polydipsia, anorexia, vomiting, and recurrent bleeding from the gums. Fundoscopy showed the typical retinal changes associated with this syndrome. A polymeric IgA cryoglobulin characterized in the dog's serum was later isolated and structurally studied. It was found to contain J chain but no secretory component. The heavy and light chains were covalently bound. |
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Authors:
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G Virella; R J Slappendel; J Goudswaard |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: International archives of allergy and applied immunology Volume: 55 ISSN: 0020-5915 ISO Abbreviation: Int. Arch. Allergy Appl. Immunol. Publication Date: 1977 |
Date Detail:
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Created Date: 1978-02-23 Completed Date: 1978-02-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0404561 Medline TA: Int Arch Allergy Appl Immunol Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 537-41 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Viscosity* Cryoglobulins* Dogs Electrophoresis, Polyacrylamide Gel Immunoelectrophoresis Immunoglobulin A* Male Multiple Myeloma / complications*, pathology Paraproteinemias / complications*, pathology Secretory Component |
| Chemical | |
Reg. No./Substance:
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0/Cryoglobulins; 0/Immunoglobulin A; 0/Secretory Component |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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