Document Detail

Multiple microembolic borderzone brain infarctions and endomyocardial fibrosis in idiopathic hypereosinophilic syndrome and in Schistosoma mansoni infestation.
MedLine Citation:
PMID:  14742613     Owner:  NLM     Status:  MEDLINE    
We report two cases of multiple distal borderzone ischaemic strokes associated with hypereosinophilia due to idiopathic hypereosinophilic syndrome in one patient and to acute Schistosoma mansoni infestation in the other. Endomyocardial fibrosis (EMF) was documented pathologically, in one case at autopsy and in the other after cardiac surgery; and by cardiac CT, with initially negative echocardiography, in one patient. These observations suggest that so called borderzone infarcts may be due to microembolisms and that, in the context of hypereosinophilia, EMF diagnosis warrants complete cardiac investigation including cardiac CT and repeat echocardiography.
M Sarazin; E Caumes; A Cohen; P Amarenco
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  75     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-01-26     Completed Date:  2004-03-11     Revised Date:  2008-11-20    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  305-7     Citation Subset:  IM    
Department of Psychogeriatrics, Bretonneau Hospital, Paris, France.
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MeSH Terms
Brain / blood supply*,  microbiology,  pathology
Cerebral Infarction / etiology*,  pathology
Endomyocardial Fibrosis / complications*,  radiography
Heart / radiography
Hypereosinophilic Syndrome / complications*,  diagnosis
Intracranial Embolism / complications*,  pathology
Magnetic Resonance Imaging
Middle Aged
Schistosoma mansoni / isolation & purification
Schistosomiasis / complications*,  diagnosis,  microbiology
Tomography, X-Ray Computed

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