Document Detail


Multiple mechanisms of reactive hyperemia in arterioles of the hamster cheek pouch.
MedLine Citation:
PMID:  7304764     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To investigate mechanisms of reactive hyperemia, single arterioles of the hamster cheek pouch were occluded for periods of 1 s-3 min. Arteriolar diameters were measured upstream and downstream from the occlusion. O2 availability to the tissue was controlled by equilibrating the suffusate with low (0% O2) or high (10% O2) O2 gas mixtures. After very brief occlusions downstream sites dilated transiently, but upstream diameters did not change. Upstream and downstream diameters both increased during longer occlusions with O%-O2 and 10%-O2 suffusion. Microvascular pressure decreased at downstream sites and increased at upstream sites within 1-2 s of occlusion. During 0%-O2 suffusion tissue and periarteriolar O2 tensions (PO2's) began to decrease within 2 s of occlusion and had decreased halfway to their minimum value by 7 s. PO2's decreased only slightly during 10%-O2 suffusion. Calculated first-order rate constants for arteriolar diameter recovery decreased and total recovery time increased as occlusion duration was prolonged. This study suggests that multiple mechanisms (metabolic, myogenic, and passive) contribute to reactive hyperemia.
Authors:
J H Lombard; B R Duling
Related Documents :
8549574 - Dynamics of anaerobic and aerobic energy supplies during sustained high intensity exerc...
6369064 - Metabolic bases of excess post-exercise oxygen consumption: a review.
14974724 - Oxygen triggering reversible modulation of vibrio fischeri strain y1 bioluminescence in...
10759604 - Endogenous nitric oxide in the control of skeletal muscle oxygen extraction during exer...
9512844 - 40 hz auditory steady-state response and eeg spectral edge frequency during sufentanil ...
17029304 - Is the loudness dependence of auditory evoked potentials modulated by the selective ser...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of physiology     Volume:  241     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1981 Nov 
Date Detail:
Created Date:  1982-01-28     Completed Date:  1982-01-28     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  H748-55     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Arteries / physiopathology*
Cheek / blood supply
Cricetinae
Hyperemia / physiopathology*
Kinetics
Mesocricetus
Mouth / blood supply*
Oxygen / blood
Partial Pressure
Pressure
Grant Support
ID/Acronym/Agency:
HL-05026/HL/NHLBI NIH HHS; HL-12792/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Estimates of isogravimetric capillary pressures during alveolar hypoxia.
Next Document:  Perinatal pulmonary prostaglandin production.