Document Detail

Multiple malignant and benign lesions in the liver in a child with adrenocortical carcinoma.
MedLine Citation:
PMID:  18256815     Owner:  NLM     Status:  MEDLINE    
We report 4-year-old girl who was diagnosed with adrenocortical carcinoma when she was 2 years old. At the time of diagnosis there were no metastases, but 6 months later multiple liver metastases appeared. Following intensive chemotherapy the metastases resolved completely. Multifocal lesions were detected in the liver by US 16 months later. Their morphology on US and MRI differed from the previous metastases. Histopathological examination confirmed focal nodular hyperplasia. We discuss the origin and the uncommon appearance of multifocal nodular hyperplasia in hormone-active tumours such as adrenocortical carcinoma in children.
Ina Sorge; Uta Bierbach; Rainer Finke; Wolfgang Hirsch
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-02-07
Journal Detail:
Title:  Pediatric radiology     Volume:  38     ISSN:  0301-0449     ISO Abbreviation:  Pediatr Radiol     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-04-08     Completed Date:  2008-11-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0365332     Medline TA:  Pediatr Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  588-91     Citation Subset:  IM    
Department of Paediatric Radiology, University of Leipzig, Liebigstrasse 20a, 04103 Leipzig, Germany.
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MeSH Terms
Adrenal Cortex Neoplasms / pathology*,  surgery
Adrenocortical Carcinoma / pathology*,  surgery
Antineoplastic Combined Chemotherapy Protocols / adverse effects*,  therapeutic use
Child, Preschool
Diagnosis, Differential
Focal Nodular Hyperplasia / chemically induced,  diagnosis*
Liver / pathology,  ultrasonography
Liver Neoplasms / diagnosis*,  drug therapy,  secondary
Magnetic Resonance Imaging / methods
Rare Diseases

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