| Multiple leiomyoma as a possible sign of aggressive renal cancer. | |
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MedLine Citation:
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PMID: 18986449 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 53-year-old Chinese man presented with a history of painful lesions on the chest of 20 years' duration. He experienced sharp pain especially on touching and after spicy food. The lesions were stable with no increase in size or number. He was otherwise well. There was no significant family history. Physical examination revealed multiple, grouped, pink papules on the left chest, extending to the right back in a segmental distribution, each measuring 2-5 mm (Figs 1 and 2). They appeared pearly and keloid-like, and had a firm consistency. A punch biopsy specimen was obtained and sent for histopathologic examination (Figs 3 and 4). This revealed a circumscribed, nonencapsulated tumor with a Grenz zone below the epidermis. It was composed of interlacing fascicles of bland spindle cells with elongated nuclei and blunt ends, typical of a cutaneous leiomyoma. The patient subsequently underwent computed tomography of the abdomen, which did not show any renal or abdominal masses. |
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Authors:
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Min-Wee Chia; Yong-Kwang Tay; Suat-Hoon Tan |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: International journal of dermatology Volume: 47 ISSN: 1365-4632 ISO Abbreviation: Int. J. Dermatol. Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-11-06 Completed Date: 2009-03-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0243704 Medline TA: Int J Dermatol Country: United States |
Other Details:
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Languages: eng Pagination: 1157-8 Citation Subset: IM |
Affiliation:
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Division of Dermatology, Changi General Hospital, and National Skin Centre, Singapore. chia_min_wee@yahoo.com.sg |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Carcinoma, Renal Cell
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diagnosis,
genetics* Fumarate Hydratase / genetics* Genetic Predisposition to Disease Germ-Line Mutation Humans Kidney Neoplasms / diagnosis, genetics* Leiomyoma / genetics, pathology* Male Middle Aged Neoplasms, Multiple Primary / genetics, pathology* Skin Neoplasms / genetics, pathology* Thorax |
| Chemical | |
Reg. No./Substance:
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EC 4.2.1.2/Fumarate Hydratase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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