| Multiple inverted follicular keratoses as a presenting sign of Cowden's syndrome: case report with human papillomavirus studies. | |
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MedLine Citation:
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PMID: 15337985 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Inverted follicular keratosis is characterized by a squamous epithelial expansion of the infundibular portion of the hair follicle in an exophytic and endophytic pattern. The lesion is often associated with squamous eddies similar to an irritated keratosis and may have a superficial papillomatous architecture. The lesion most often arises as a solitary nodule on the face of middle age to elderly individuals. Inverted follicular keratosis has been described as a distinct entity by some while others believe that it is related to trichilemmomas and/or verruca vulgares. The cutaneous pathology of Cowden's syndrome is characterized by multiple trichilemmomas. We present a woman who fulfills the clinical criteria for Cowden's syndrome and who initially presented with multiple inverted follicular keratoses. Also, in situ hybridization studies performed on the patient's keratoses do not reveal evidence of human papillomavirus infection. |
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Authors:
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Steven M Ruhoy; Doug Thomas; Gerard J Nuovo |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of the American Academy of Dermatology Volume: 51 ISSN: 1097-6787 ISO Abbreviation: J. Am. Acad. Dermatol. Publication Date: 2004 Sep |
Date Detail:
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Created Date: 2004-08-31 Completed Date: 2005-03-17 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 7907132 Medline TA: J Am Acad Dermatol Country: United States |
Other Details:
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Languages: eng Pagination: 411-5 Citation Subset: IM |
Affiliation:
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Department of Pathology, Sunrise Hospital and Medical Center, USA. ruhoy@lasvegaspathologist.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Breast Neoplasms
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pathology Carcinoma, Basal Cell / pathology Carcinoma, Intraductal, Noninfiltrating / pathology DNA Probes, HPV Darier Disease / etiology* Facial Dermatoses / etiology, pathology Female Genetic Predisposition to Disease Goiter, Nodular / complications Hamartoma Syndrome, Multiple / complications, diagnosis* Humans Melanoma / pathology Middle Aged Neoplasms, Multiple Primary / pathology Scalp / pathology Skin Neoplasms / pathology Tongue Diseases / etiology, pathology |
| Chemical | |
Reg. No./Substance:
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0/DNA Probes, HPV |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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