Document Detail


Multiple informants: mortality associated with psychiatric disorders in the Stirling County Study.
MedLine Citation:
PMID:  11581099     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This paper applies new statistical procedures for analyzing multiple-source information about the relation of psychiatric diagnoses to mortality. The data come from the Stirling County Study, a longitudinal community investigation of adults, that collected multiple-source reports (self-report and physician-report) about psychiatric disorders. These reports are used as predictors of mortality risk over a 16-year follow-up period (1952-1968). Despite extensive efforts, one or both of these reports were sometimes missing. Missingness of self-report was related to demographic characteristics as well as to physician-reports of psychiatric diagnosis. The statistical procedures used here draw together into a single frame of reference both informant reports for the initial Stirling survey and relate these to mortality risk using weighted generalized estimating equation regression models for time to event data. This unified method has two advantages over traditional approaches: 1) the relative predictiveness of each informant can be assessed and 2) all subjects contribute to the analysis. The methods are applicable to other areas of epidemiology where multiple informant reports are used. The results for self-reports and physician-reports of disorders were comparable: Psychiatric diagnosis was associated with higher mortality, particularly among younger subjects.
Authors:
N J Horton; N M Laird; J M Murphy; R R Monson; A M Sobol; A H Leighton
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of epidemiology     Volume:  154     ISSN:  0002-9262     ISO Abbreviation:  Am. J. Epidemiol.     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2001-10-02     Completed Date:  2001-10-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7910653     Medline TA:  Am J Epidemiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  649-56     Citation Subset:  IM    
Affiliation:
Department of Epidemiology and Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA. horton@bu.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Data Collection
Epidemiologic Methods
Family Practice
Female
Follow-Up Studies
Humans
Interviews as Topic
Likelihood Functions
Logistic Models
Male
Mental Disorders / mortality*
Middle Aged
Risk Factors
Self Disclosure
Survival Analysis
Grant Support
ID/Acronym/Agency:
R01-MH39576/MH/NIMH NIH HHS; R01-MH54693/MH/NIMH NIH HHS; T32-MH17119/MH/NIMH NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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