Document Detail


Multiple familial lipomatosis with polyneuropathy, an inherited dominant condition.
MedLine Citation:
PMID:  9037345     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 22-year-old man had polyneuropathy, facial dysmorphia, atopia and multiple lipomatosis. His mother had neuropathy but not lipomatosis as two of her first cousins. The proband's grandmother had multiple lipomatosis as her own mother and a sister of her mother, but they didn't have neuropathy. This family is an example of a dominant syndrome the principle features of which are polyneuropathy. Variable expression could account for the phenotypic differences, combined with multiple lipomatosis.
Authors:
C Stoll; Y Alembik; M Truttmann
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annales de génétique     Volume:  39     ISSN:  0003-3995     ISO Abbreviation:  Ann. Genet.     Publication Date:  1996  
Date Detail:
Created Date:  1997-04-01     Completed Date:  1997-04-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370562     Medline TA:  Ann Genet     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  193-6     Citation Subset:  IM    
Affiliation:
Institut de Puériculture, Strasbourg, France.
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MeSH Terms
Descriptor/Qualifier:
Adult
Genes, Dominant*
Humans
Lipomatosis, Multiple Symmetrical / genetics*
Male
Pedigree
Peripheral Nervous System Diseases / genetics*
Phenotype

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