| Multiple endocrine neoplasias. | |
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MedLine Citation:
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PMID: 10845096 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The multiple endocrine neoplasia syndromes form a distinct group of genetic tumor syndromes. They include multiple endocrine neoplasia types 1 and 2, von Hippel Lindau syndrome, neurofibromatosis, and Carney complex. Research over the past decade has identified a molecular basis for each of these syndromes. This knowledge has revolutionized not only the clinical management but also has illuminated the field of human cancer research by the identification of new and important genes critical for regulation of cell growth, differentiation, and death. This review focuses on the structure, physiologic function, and molecular abnormalities of the genes involved in these syndromes. |
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Authors:
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A O Hoff; G J Cote; R F Gagel |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Annual review of physiology Volume: 62 ISSN: 0066-4278 ISO Abbreviation: Annu. Rev. Physiol. Publication Date: 2000 |
Date Detail:
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Created Date: 2000-09-18 Completed Date: 2000-09-18 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0370600 Medline TA: Annu Rev Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 377-411 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine Specialties, University of Texas M.D. Anderson Cancer Center, Houston 77030, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Humans Multiple Endocrine Neoplasia / genetics*, pathology Multiple Endocrine Neoplasia Type 1 / genetics Mutation / genetics |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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