| Multiple endocrine neoplasia--introduction. | |
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MedLine Citation:
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PMID: 15606371 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Each multiple endocrine neoplasia (MEN) syndrome expresses striking features of hormone oversecretion from its own characteristic group of tissues. Additional expressions include non-hormonal tumours in each MEN syndrome and selected cancers in some syndromes. The complexity of its stereotyped features results in difficult management issues that often justify cooperation across multiple specialties. MEN syndromes, though rare, have long received intense study as models for more common diseases. The syndromal nature often with a large pedigree has promoted recent discovery of the main gene that differs for each of the six MEN syndromes. Each mutant gene has been introduced into clinical decision-making and into further clarification of tumorigenesis. This mini-symposium is related to the 9th International Workshop on Multiple Endocrine Neoplasia in June 2004; it consists of six manuscripts. They report new developments in clinical practices and in basic understandings about this rapidly advancing field. |
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Authors:
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S J Marx; C A Stratakis |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of internal medicine Volume: 257 ISSN: 0954-6820 ISO Abbreviation: J. Intern. Med. Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2004-12-20 Completed Date: 2005-02-14 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 8904841 Medline TA: J Intern Med Country: England |
Other Details:
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Languages: eng Pagination: 2-5 Citation Subset: IM |
Affiliation:
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Metabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA. stephenm@intra.niddk.nih.gov |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Genotype Humans Hyperparathyroidism / complications Multiple Endocrine Neoplasia / genetics, physiopathology, therapy* Mutation Patient Care Team Phenotype |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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