| Multiple endocrine neoplasia in a dog. | |
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MedLine Citation:
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PMID: 11032679 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Multiple endocrine neoplasms, including an insulinoma, bilateral adrenocortical adenocarcinomas and an aortic paraganglioma, were diagnosed after euthanasia in a 12-year-old spayed female dog of mixed breed with a history of progressive anorexia, vomiting, diarrhoea, weight loss, polyuria and polydipsia, regenerative anaemia and hypoglycaemia. The clinical, gross pathological, microscopical, immunohistochemical and ultrastructural findings were consistent with the human syndrome of multiple endocrine neoplasia. |
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Authors:
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M Kiupel; P B Mueller; J Ramos Vara; A Irizarry; T L Lin |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of comparative pathology Volume: 123 ISSN: 0021-9975 ISO Abbreviation: J. Comp. Pathol. Publication Date: 2000 Aug-Oct |
Date Detail:
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Created Date: 2000-11-03 Completed Date: 2000-11-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0102444 Medline TA: J Comp Pathol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 210-7 Citation Subset: IM |
Copyright Information:
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Copyright 2000 Harcourt Publishers Ltd. |
Affiliation:
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Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, IN 47907, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Gland Neoplasms
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metabolism,
pathology*,
ultrastructure Animals Chromogranin A Chromogranins / analysis Dogs Fatal Outcome Female Immunohistochemistry Insulin / analysis Microscopy, Electron Multiple Endocrine Neoplasia / metabolism, pathology*, ultrastructure Pancreatic Neoplasms / metabolism, pathology*, ultrastructure Paraganglioma / metabolism, pathology*, ultrastructure Phosphopyruvate Hydratase / analysis S100 Proteins / analysis Somatostatin / analysis Synaptophysin / analysis |
| Chemical | |
Reg. No./Substance:
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0/Chromogranin A; 0/Chromogranins; 0/S100 Proteins; 0/Synaptophysin; 11061-68-0/Insulin; 51110-01-1/Somatostatin; EC 4.2.1.11/Phosphopyruvate Hydratase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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