Document Detail


Multiple endocrine adenomas in a patient with the Maffucci syndrome.
MedLine Citation:
PMID:  12657     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A patient with multiple cutaneous hemangiomas and skeletal dyschondroplasia (the Maffucci syndrome) was found to have a pituitary chromophobe adenoma, a parathyroid adenoma and two other neoplasms. The presence of two endocrine tumors suggested the syndrome of multiple endocrine adenomatosis, and raised the issue of an etiologic relationship between this disease and the Maffucci syndrome. Dyschondroplasia, however, has no known influence on the secretion of parathyroid hormone or any of the pituitary hormones. The Maffucci syndrome is associated with a high incidence of malignancy, but it involves primarily mesodermal derivatives whereas multiple endocrine adenomatosis affects tissues of ectodermal origin. The association of the two in our patient is probably fortuitous.
Authors:
A M Schnall; S M Genuth
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of medicine     Volume:  61     ISSN:  0002-9343     ISO Abbreviation:  Am. J. Med.     Publication Date:  1976 Dec 
Date Detail:
Created Date:  1977-02-24     Completed Date:  1977-02-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  952-6     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adenoma, Chromophobe / complications
Adolescent
Adult
Angiomatosis / complications*
Child
Child, Preschool
Female
Hemangioma / complications
Humans
Hypercalcemia / complications
Infant
Infant, Newborn
Male
Multiple Endocrine Neoplasia / complications*
Neoplasms, Multiple Primary / complications*
Neurilemmoma / complications
Osteochondrodysplasias / complications*,  radiography
Parathyroid Neoplasms / complications
Peripheral Nervous System Neoplasms / complications
Pituitary Neoplasms / complications
Radiography, Thoracic
Skin Neoplasms / complications*
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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