Document Detail


Multiple cranial neuropathy variant of guillain-barré syndrome: A case series.
MedLine Citation:
PMID:  21698648     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
INTRODUCTION: Prompt identification of the rare cranial variant of Guillain-Barré syndrome (GBS) is crucial, but the clinical characteristics remain poorly defined. METHODS: We conducted a retrospective review of 12 GBS patients hospitalized from 1995 to 2009 with multiple cranial nerve (CN) impairment at disease onset. RESULTS: Eight patients had impairment of CN IX and X; 3 of CN VII; and 1 of CN VII, IX, and X. All patients had areflexia or hyporeflexia, 6 had Lasegue sign, and 5 required tracheostomy and mechanical ventilation. All patients had cerebrospinal fluid (CSF) albuminocytologic dissociation within 2-3 weeks after onset. Electrophysiological studies showed motor conduction velocity and F-wave abnormalities in 10 of 12 and 10 of 11 patients, respectively. Treatment with intravenous immunoglobulin was effective. CONCLUSIONS: Bilateral CN IX, X, and/or VII impairment with areflexia or hyporeflexia, early abnormal F-wave response, nerve conduction abnormalities, and CSF albuminocytologic dissociation support a diagnosis of this GBS cranial variant. Muscle Nerve, 2011.
Authors:
Qingsong Wang; Yang Xiang; Ke Yu; Congyang Li; Jun Wang; Li Xiao
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-1
Journal Detail:
Title:  Muscle & nerve     Volume:  -     ISSN:  1097-4598     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-6-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7803146     Medline TA:  Muscle Nerve     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Wiley Periodicals, Inc.
Affiliation:
Department of Neurology, Chengdu Military General Hospital, Tianhui Road 270, Rongdu Street, Chengdu 610083, China; Electrophysiological Laboratory, Chengdu Military General Hospital, Chengdu, China. wqs832001@sina.com.
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