Document Detail

Multiple cranial nerve enhancement in mitochondrial neurogastrointestinal encephalomyopathy.
MedLine Citation:
PMID:  20351514     Owner:  NLM     Status:  MEDLINE    
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare disease that often presents with nonspecific white matter abnormalities on magnetic resonance imaging. Ptosis and ophthalmoparesis are a part of its clinical features. We report multiple cranial nerve contrast enhancement on magnetic resonance imaging in a patient with MNGIE and postulate that demyelination may be the responsible substrate for this previously unreported finding. This finding may also explain the cranial neuropathies that patients with MNGIE have.
Sasitorn Petcharunpaisan; Mauricio Castillo
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  34     ISSN:  1532-3145     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    2010 Mar-Apr
Date Detail:
Created Date:  2010-03-30     Completed Date:  2010-05-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  247-8     Citation Subset:  IM    
Department of Radiology, UNC Hospital, Chapel Hill, NC, USA.
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MeSH Terms
Cachexia / pathology
Cranial Nerves / pathology*
Diagnosis, Differential
Gastrointestinal Diseases / pathology*
Magnetic Resonance Imaging / methods*
Mitochondrial Encephalomyopathies / pathology*

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