Document Detail

Multiple congenital septal atresias of the intestine: histomorphologic and pathogenetic implications.
MedLine Citation:
PMID:  6687294     Owner:  NLM     Status:  MEDLINE    
Congenital atresias of the gastrointestinal tract are usually single and divided into three forms on a morphologic basis. The septal or diaphragmatic type (type I) is the least common. We report an infant with multiple type I atresias involving both the small and large intestine and describe the unique histologic features of the septa: fragmentation of muscularis mucosa, multiple septal cysts lined by columnar epithelium, circular and longitudinal muscular layers, and absence of inflammation. This infant had a sibling who died with multiple intestinal atresias of the septal type. The histologic features suggest that type I gastrointestinal atresias may be due to failure of complete recanalization rather than result from healing of vascular of inflammatory events.
K J Kao; R Fleischer; W D Bradford; B H Woodard
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric pathology / affiliated with the International Paediatric Pathology Association     Volume:  1     ISSN:  0277-0938     ISO Abbreviation:  Pediatr Pathol     Publication Date:    1983 Oct-Dec
Date Detail:
Created Date:  1984-12-06     Completed Date:  1984-12-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8303527     Medline TA:  Pediatr Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  443-8     Citation Subset:  IM    
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MeSH Terms
Abnormalities, Multiple
Colon / abnormalities*,  pathology
Duodenal Obstruction / congenital
Infant, Newborn
Intestinal Atresia / embryology,  pathology*
Jejunum / abnormalities,  pathology

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